The Challenge
More than 90% of drug candidates fail. Not because they’re ineffective, but because they never reach the right place in the body or trigger harmful side effects. These failures cost billions, delay care, and leave patients without answers.
While AI is speeding up early-stage discovery—like molecule design and target selection—it can’t yet predict what truly determines a drug’s success: how it moves through the body and whether it causes harm.
That’s where the Institute comes in.
Our Vision
We’re bridging the gap between discovery and success for tomorrow’s medicines.
Our Mission
Build predictive and generative models to make drug development faster, safer, and more precise.
What We’re Building
AI-Powered Tools
Developing machine-learning models that forecast how drugs move through the body and predict potential toxicity—well before clinical trials.
Smarter Molecule Design
Leveraging generative AI to guide the creation of new, more effective therapeutic modalities.
Regional Expertise Hub
Establishing the Pacific Northwest as a leader in drug disposition and delivery science.
Training Tomorrow’s Leaders
Launching interdisciplinary programs for graduate students and postdocs at the intersection of AI, pharmaceutical sciences, and drug delivery.
Scaling Impact: From Molecule to Medicine
Build Training Sets
Peptides, Antibodies, and other Biologics
Predict Factors
AI / ML tools to predict key properties
Predict Drug Developability
AI-enabled PBPK Models
Generate New Molecule
GenAI-enabled models design new molecules with IP and spinoff potential
Collaborators & Partners
UW is uniquely positioned—leveraging decades of leadership in metabolism/PK-PD, nationally ranked programs, and deep ties with partners such as Fred Hutch and the Institute for Protein Design—to serve as a regional and national hub for AI-enabled drug disposition and delivery.